Dell PowerEdge R7625 Server: AMD EPYC Power, Specs and Best-Fit Workloads Explained

The Dell PowerEdge R7625 is Dell’s 2U, dual-socket flagship built on AMD EPYC processors. Supporting 4th and 5th Generation AMD EPYC chips with up to 128 cores per socket, 24 DDR5 DIMM slots reaching 6 TB, PCIe Gen5 expansion and up to 24 NVMe drive bays, it is the highest-density general-purpose server in the PowerEdge 2U lineup — and the natural answer when the workload is core-count- and memory-bandwidth-hungry. This guide covers the full R7625 specification set, what the AMD EPYC architecture changes in practice, how it compares with the Intel-based PowerEdge R760, and the workloads where it earns its rack space fastest.

What Is the Dell PowerEdge R7625?

The R7625 belongs to Dell’s 16th-generation PowerEdge family and is the AMD counterpart to the Intel-based R760. Where the R760 maximizes per-core performance and ecosystem breadth, the R7625 leans on EPYC’s defining advantages: very high core counts per socket, 12 memory channels per CPU, and a large number of PCIe 5.0 lanes straight from the processor. The result is a 2U server that consolidates more virtual machines, more VDI sessions and more storage spindles per chassis than almost anything else in its class.

PowerEdge R7625 Specifications

Item	Specification
Form factor	2U rack server
Processors	1-2 x 4th Gen AMD EPYC 9004 (Genoa/Bergamo) or 5th Gen AMD EPYC 9005 (Turin), up to 128 cores per socket (256 cores / 512 threads per system), Socket SP5, xGMI interconnect
Memory	24 x DDR5 RDIMM slots, up to 6 TB, up to 4800 MT/s (5600 MT/s DIMMs are clocked to the platform maximum)
Drive bays	Up to 24 x 2.5-inch SAS/SATA/NVMe (368.64 TB), 12 x 3.5-inch SAS/SATA, or 32 x EDSFF E3.S NVMe; rear bays for 2-4 x 2.5-inch or 4 x E3.S
Boot device	BOSS-N1 (hardware RAID 2 x M.2 NVMe)
Storage controllers	PERC H965i, H755, HBA465e; software RAID options
PCIe expansion	Up to 8 PCIe slots (Gen5/Gen4 mix), plus OCP 3.0 slot
GPU support	Up to 2 x 300 W double-width or 6 x 75 W single-width GPUs
Network	Optional 2 x 1GbE LOM plus OCP 3.0 (up to 400 GbE)
Power supplies	Hot-plug redundant 800 W to 3200 W, Platinum and Titanium options
Cooling	Air cooling or optional Direct Liquid Cooling (DLC)
Management	iDRAC9, Redfish RESTful API, OpenManage Enterprise, CloudIQ
Security	AMD SME and SEV memory encryption, Silicon Root of Trust, signed firmware, Secure Boot, TPM 2.0 (FIPS/CC-TCG), System Lockdown, SED encryption
Operating systems	Windows Server with Hyper-V, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, Ubuntu Server LTS, VMware ESXi

What the AMD EPYC Architecture Delivers

Up to 256 cores and 512 threads in 2U

Two EPYC 9004/9005 processors push core density well beyond what the Intel-based R760 offers per socket. For license-sensitive workloads — hypervisors, databases, VDI — doubling cores per 2U chassis directly reduces rack count, power draw and per-socket software licensing.

12 memory channels per socket

Each EPYC CPU drives 12 DDR5 channels, and the R7625 exposes 24 DIMM slots across two sockets. Memory bandwidth scales with core count, which is precisely what large VM farms, SAP HANA-class databases and in-memory analytics need. Total capacity reaches 6 TB of registered ECC DDR5.

Gen5 I/O straight from the CPU

EPYC’s biggest structural advantage is the sheer number of processor-native PCIe 5.0 lanes. In the R7625 they feed up to eight expansion slots, OCP 3.0 networking at up to 400 GbE, and up to 24 NVMe U.2 drives — or 32 EDSFF E3.S modules — without PLX switching overhead.

Storage layouts for every strategy

Three front-bay architectures (24 x 2.5-inch, 12 x 3.5-inch, or 32 x E3.S) plus rear expansion let the same chassis serve as an all-flash virtualization node, a capacity-tier SDS building block, or a dense NVMe cache tier. PERC H965i provides hardware RAID with NVMe acceleration, and BOSS-N1 keeps the OS on mirrored M.2.

Security built into the silicon

Beyond Dell’s standard Silicon Root of Trust, signed firmware and System Lockdown, the AMD platform adds hardware memory encryption through AMD SME and confidential computing via SEV — a differentiator for multi-tenant cloud and regulated-industry workloads.

Thermal design up to liquid cooling

High-TDP EPYC SKUs and GPU options are supported by air cooling in most configurations, with optional Direct Liquid Cooling for the hottest builds. Titanium-rated PSUs scale to 3200 W in hot-plug redundant pairs.

R7625 vs R760: AMD or Intel?

Feature	PowerEdge R7625 (AMD)	PowerEdge R760 (Intel)
Max cores per socket	128 (EPYC 9004/9005)	64 (5th Gen Xeon)
Max cores per system	256	128
Memory channels	12 per socket	8 per socket
Memory	24 DDR5 slots, up to 6 TB	32 DDR5 slots, up to 8 TB
PCIe slots	Up to 8 (Gen5/Gen4)	Up to 8 (multiple Gen5 x16)
Max drives	24 x 2.5″ or 32 x E3.S	24 x 2.5″ + rear bays
GPU support	2 x 300 W DW / 6 x 75 W SW	2 x 350 W DW / 6 x 75 W SW
Confidential computing	AMD SEV/SME built in	Intel TDX (select SKUs)

The decision rule is simple. If the constraint is core count and memory bandwidth per rack unit — dense virtualization, VDI, HPC, big data — the R7625 usually wins on cores per watt and per license. If the workload depends on max per-core clock speed, DDR5 capacity ceiling (8 TB) or a specific Intel-ecosystem certification, the R760 remains the better fit. Dell-cited generation-over-generation figures for the R7625 include +36% SPECrate2017 int performance and +36% VDI desktop density versus the previous AMD generation, with all-flash IOPS up about 33%.

Best-Fit Workloads

• Dense server virtualization and private cloud (VMware vSphere, Hyper-V, KVM)

• VDI and end-user computing consolidation

• Big data, data lakes and real-time analytics

• Databases and in-memory platforms (SAP HANA, SQL Server, PostgreSQL)

• HPC and simulation clusters

• Software-defined storage and all-flash SDS

• AI inference and GPU-accelerated analytics

Frequently Asked Questions

How many cores does the Dell PowerEdge R7625 support? Two AMD EPYC 9004 or 9005 processors with up to 128 cores each, for a maximum of 256 cores and 512 threads per 2U server.

How much memory does the R7625 hold? 24 DDR5 RDIMM slots with a maximum of 6 TB, running at up to 4800 MT/s. DIMMs rated higher are clocked down to the platform maximum.

Does the R7625 support GPUs? Yes — up to two 300 W double-width cards or six 75 W single-width accelerators, with Gen5 lanes available for NVIDIA L40S-class and similar PCIe GPUs. For dense GPU builds, Dell’s GPU-dedicated PowerEdge models are the better fit.

What is the difference between the R7625 and the R760? The R7625 is the AMD EPYC platform: more cores per socket (128 vs 64), 12 memory channels per CPU and built-in SEV/SME encryption. The R760 is the Intel platform: higher memory ceiling (8 TB), strong per-core performance and broader legacy certification. Choose by workload profile, not brand.

Does the R7625 support direct liquid cooling? Yes. Direct Liquid Cooling is optional for the highest-TDP EPYC configurations, alongside standard air cooling with Dell’s optimized airflow design.